Randomised, double‑blind, placebo‑controlled design across seven research sites
500 mg of Ashwagandha extract (equivalent to four grams of raw root) taken daily
86 % (1,032) participants completed the trial
No evidence of liver or kidney injury; all safety labs stayed normal
Vaccine‑induced neutralising activity remained above 85 % in both groups
Liver and kidney function remained within normal ranges, and no serious adverse events were linked to the supplement.
The supplement did not reduce the neutralising antibody response to the COVID‑19 vaccine.
Results support the safety of this herbal preparation when used alongside vaccination.
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